Комбинирование соединений Cu (II) с восстановителями для преодоления лекарственной устойчивости опухолевых клеток
Савин А. М., Болдырихин А. Ю., Татарский В. В., Штиль А. А. Костномозговое микроокружение снижает эффективность мишен-направленного воздействия на клетки хронического миелоидного лейкоза: экспериментальная модель для поиска терапевтических комбинаций //
Shtil A.A., Chernov K.V., Tsymbal S.A. Cell Death by Metals: Diversity of Phenomena vs. Distinctive Categories. Cancers. 2024. Vol. 16. No. 22. pp. 3767.
Beloglazkina E., Moiseeva A., Tsymbal S.A., Guk D., Kuzmin M.A., Krasnovskaya O., Borisov R.S., Barskaya E.S., Tafeenko V.A., Alpatova V., Zaitsev A.V., Finko A.V., Ol'Shevskaya V.A., Shtil A.A. The Copper Reduction Potential Determines the Reductive Cytotoxicity: Relevance to the Design of Metal–Organic Antitumor Drugs. Molecules. 2024. Vol. 29. No. 5. pp. 1032.
A Novel Chemotype of Cyclin Dependent Kinase Inhibitors Potent for Neuroblastoma Cells
МАТЕРИАЛЫ IX Всероссийской конференции по молекулярной онкологии 18–20 декабря 2024 г., Москва
Kuchur O.A., Zavisrskiy A.V., Shtil А. Transcriptional Reprogramming Regulates Tumor Cell Survival in Response to Ionizing Radiation: a Role of p53. Bulletin of Experimental Biology and Medicine. 2023. Vol. 174. No. 5. pp. 659-665.
Rusina P., Lisov A., Denisova A., Gandalipov E.R., Novikov F., Shtil A.A. Clinical CDK2 Inhibitors: Trends to Selectivity and Efficacy. Recent Patents on Anti-cancer Drug Discovery. 2023. Vol. 18. No. 2. pp. 102-107.
Kokinos E.K., Tsymbal S.A., Galochkina A.V., Bezlepkina S.A., Nikolaeva J.V., Vershinina S.O., Shtro A., Tatarskiy V.V., Shtil A.A., Broude E.V., Roninson I.B., Dukhinova M. Inhibition of Cyclin-Dependent Kinases 8/19 Restricts Bacterial and Virus-Induced Inflammatory Responses in Monocytes. Viruses. 2023. Vol. 15. No. 6. pp. 1292.
Guk D., Gibadullina K.R., Burlutskiy R.O., Pavlov K.G., Moiseeva A., Tafeenko V.A., Lyssenko K.A., Gandalipov E.R., Shtil A., Beloglazkina E. New Titanocene (IV) Dicarboxylates with Potential Cytotoxicity: Synthesis, Structure, Stability and Electrochemistry. International Journal of Molecular Sciences. 2023. Vol. 24. No. 4. pp. 3340.
Моделирование резистентности хронического миелоидного лейкоза к ингибиторам BCR-ABL в костном мозге
Кокинос Е.К., Кузьмина Д., Кучур О.А., Цымбал С.А., Василичин В.А., Галочкина А.В., Завирский А.В., Башарин В.А., Штро А.А., Штиль А.А., Духинова М.С. Фенотипический и функциональный анализ линии моноцитов THP-1 как модели воспаления [Phenotypic and functional characteristic analysis of THP-1 cell line as a model of inflammation]. Иммунология [Immunologiya]. 2022. Т. 43. № 3. С. 277-287.
Ингибирование СDK8/19-зависимого перепрограммирования транскрипции - новый механизм радиосенситизации p53-положительных опухолевых клеток
Цымбал С.А., Штиль А.А. Исследование переносимости медьсодержащих соединений и восстановителя для разработки модели терапии опухолевого асцита. Вопросы онкологии [Voprosy Onkologii]. 2022. Т. 68. № S3. С. 361-362.
Определение цитотоксической и противоопухолевой активности комбинации медьорганических соединений и N-ацетилцистеина на модели полостных метастазов in vivo
СИНТЕТИЧЕСКАЯ ЛЕТАЛЬНОСТЬ КЛЕТОК MYCN ПОЛОЖИТЕЛЬНОЙ НЕЙРОБЛАСТОМЫ ПОД ДЕЙСТВИЕМ СЕЛЕКТИВНЫХ ИНГИБИТОРОВ CDK2
Механизмы гибели опухолевых клеток при действии производных териндолона
Ivanov V., Agamennone M., Iusupov I.R., Laghezza A., Novoselov A.M., Manasova E.V., Altieri A., Tortorella P., Shtil А., Kurkin A.V. Het(aryl)isatin to het(aryl)aminoindoline scaffold hopping: A route to selective inhibitors of matrix metalloproteinases. Arabian Journal of Chemistry. 2022. Vol. 15. No. 1. pp. 103492.
Shutkov I., Okulova Y.N., Tyurin V.Y., Sokolova E.V., Babkov D.A., Spasov A.A., Gracheva Y.A., Schmidt G., Kirsanov K., Shtil А., Redkozubova O., Shevtsova E.F., Milaeva E.R., Ott I., Nazarov A.A. Ru (III) Complexes with lonidamine-modified ligands. International Journal of Molecular Sciences. 2021. Vol. 22. No. 24. pp. 13468.
Kuchur O.A., Kuzmina D., Dukhinova M.S., Shtil A. The p53 Protein Family in the Response of Tumor Cells to Ionizing Radiation: Problem Development. Acta Naturae (англоязычная версия). 2021. Vol. 13. No. 3. pp. 65-76.
Механизмы усиления гибели опухолевых клеток при ионизирующем излучении: связь между p53 и CDK8/19
Кучур О.А., Кучур П.Д., Кузьмина Д.О., Завирский А.В., Штиль А.А. Дифференциальная регуляция BBC3/PUMA и PMAIP1/Noxa при ионизирующем излучении: роль p53 [Differential Regulation of BBC3/PUMA and PMAIP1/Noxa by Ionizing Radiation: A Role for p53]. Цитология [Tsitologiya]. 2021. Т. 63. № 4. С. 363-372.
Attenuation of p53 signaling by CDK8/19 sensitizes tumor cells to ionizing radiation
Использование меди N-ацетилцистеином и аскорбатом для преодоления лекарственной устойчивости опухолевых клеток
ИНГИБИРОВАНИЕ p53 ЧЕРЕЗ CDK8/19 ПОВЫШАЕТ ЧУВСТВИТЕЛЬНОСТЬ ОПУХОЛЕВЫХ КЛЕТОК К ИОНИЗИРУЮЩЕМУ ИЗЛУЧЕНИЮ
РОЛЬ СТАТУСА Р53 В ОТВЕТЕ ОПУХОЛЕВЫХ КЛЕТОК НА ИОНИЗИРУЮЩЕЕ ИЗЛУЧЕНИЕ ПРИ ИНГИБИРОВАНИИ CDK8/19
65P - Oxidative stress associated with Cu2+ to Cu+ reduction for eradicating wild type and multidrug resistant tumor cells
Tsymbal S., Agadzhanyan N., Shtil А. Oxidative stress associated with Cu2+to Cu+ reduction for eradicating wild type and multidrug-resistant tumor cells. Annals of Oncology. 2021. Vol. 32. No. Suppl.6. pp. S1365-S1365.
Kuchur O.A., Kuchur P.D., Kuzmina D., Zavirsky A.V., Shtil A. Differential Regulation of BBC3/PUMA and PMAIP1/Noxa in Ionizing Radiation: the Role of p53. Cell and Tissue Biology. 2021. Vol. 15. No. 6. pp. 544-553.
Брутер А.В., Родионова М.Д., Варламова Е.А., Штиль А.А. Суперэнхансеры в регуляции транскрипции генов: общебиологические аспекты и мишени противоопухолевой терапии. Acta Naturae (русскоязычная версия). 2021. Т. 13. № 1. С. 4-15.
Tsymbal S.A., Moiseeva A., Agadzhanian N., Efimova S., Markova A.A., Guk D., Krasnovskaya O., Alpatova V., Zaitsev A.V., Shibaeva A., Tatarskiy V.V., Dukhinova M.S., Ol’Shevskaya V., Ostroumova O., Beloglazkina E., Shtil А. Copper-Containing Nanoparticles and Organic Complexes: Metal Reduction Triggers Rapid Cell Death via Oxidative Burst. International Journal of Molecular Sciences. 2021. Vol. 22. No. 20. pp. 11065.
Bruter А., Rodionova M., Varlamova Е., Shtil А. Super-Enhancers in the Regulation of Gene Transcription: General Aspects and Antitumor Targets. Acta Naturae (англоязычная версия). 2021. Vol. 13. No. 1. pp. 4-15.
Kuchur O.A., Zavirskiy A.V., Shtil А. Attenuation of p53 signaling by CDK8/19 sensitizes tumor cells to ionizing radiation. Annals of Oncology. 2021. Vol. 32. No. Suppl.6. pp. S1358-S1358.
Medvedeva G., Kuzmina D., Nuzhina J.V., Shtil A.A., Dukhinova M.S. How macrophages become transcriptionally dysregulated: A hidden impact of antitumor therapy. International Journal of Molecular Sciences. 2021. Vol. 22. No. 5. pp. 2662.
Кучур О.А., Кузьмина Д.О., Духинова М.С., Штиль А.А. Белки семейства p53 в ответе опухолевых клеток на ионизирующее излучение: развитие проблемы. Acta Naturae (русскоязычная версия). 2021. Т. 13. № 3. С. 65-76.
Gornostaev L.M., Fominykh O.I., Rukovets T.A., Lavrikova T.I., Khalyavina J.G., Shtil A., Shunaev A.V., Dunaev S.F., Murashova E.V., Chernyshev V.V. Synthesis of 6b,11b-dihydroxy-12-methylphenyl-11b,12-dihydrobenzo- [g]indeno[1,2-b]indole-5,6,7(6bH)-triones and 2-(3-hydroxy-4,9-dioxo-4,9-dihydro-1H-benzo[f]indol-2-yl)benzamides, their structure and antiproliferative activity. Chemistry of Heterocyclic Compounds. 2020. Vol. 56. No. 1. pp. 47-54.
Kotliarova M.S., Soldatenko A.S., Arkhipova A.Y., Bessonov I.V., Davydova L.I., Moysenovich A.M., Bogush V.G., Debabov V.G., Shtil A.A., Moisenovich M.M., Shaitan K.V. Photocurable Films Based on Fibroin and Gelatin for Skin Regeneration. Moscow University Biological Sciences Bulletin. 2020. Vol. 75. No. 1. pp. 20-25.
Dukhinova M.S., Shestovskaya M.V., Shtil A.A. Metal Nanoparticles in Immunotherapy: Applications, Limitations and Pespectives. Research & Development in Material Science. 2020. Vol. 12(4). No. 3. pp. 1292-1295.
Single vs Multiple Drug Targets: Revising the Therapeutic Concept to Combat Intractable Cancers
Boron-Based Compounds: Potential and Emerging Applications in Medicine
The role of p53 status in response to ionizing radiation
Moysenovich A.M., Moisenovich M.M., Sudina A.K., Tatarskiy V., Khamidullina A.I., Yastrebova M.A., Davydova L.I., Bogush V.G., Debabov V.G., Arkhipova A.Y., Shaitan K.V., Shtil A.A., Demina I.A. Recombinant Spidroin Films Attenuate Individual Markers of Glucose Induced Aging in NIH 3T3 Fibroblasts. Biochemistry (Moscow). 2020. Vol. 85. No. 7. pp. 808–819.
Tikhomirov A.S., Litvinova V., Andreeva D.V., Tsvetkov V., Dezhenkova L.G., Volodina Y.L., Kaluzhny D.N., Treshalin I., Schols D., Ramonova A.A., Moisenovich M.M., Shtil A.A., Shchekotikhin A.E. Amides of pyrrole- and thiophene-fused anthraquinone derivatives: A role of the heterocyclic core in antitumor properties. European Journal of Medicinal Chemistry. 2020. Vol. 199. pp. 112294.
Moysenovich A.M., Tatarskiy V.V., Yastrebova M.A., Bessonov I.V., Arkhipova A.Y., Kolosov A.S., Davydova L.I., Khamidullina A.I., Bogush V.G., Debabov V.G., Shaitan K.V., Shtil A.A., Moisenovich M.M. Akt and Src mediate the photocrosslinked fibroin-induced neural differentiation. NeuroReport. 2020. Vol. 31. No. 10. pp. 770–775.
Marsova M., Odorskaya M., Novichkova M., Polyakova V., Abilev S., Kalinina E., Shtil A., Poluektova E., Danilenko V. The Lactobacillus brevis 47 f strain protects the murine intestine from enteropathy induced by 5-fluorouracil. Microorganisms. 2020. Vol. 8. No. 6. pp. 876.
Vasilyeva S.V., Petrova A.S., Shtil A.A., Stetsenko D.A. Application of silicon dioxide nanoparticles modified with tumor-targeting ligands for cellular delivery of nucleoside triphosphate analogues. Journal of Saudi Chemical Society. 2020. Vol. 24. No. 1. pp. 98-104.
Kuchur O.A., Tsymbal S.A., Shestovskaya M.V., Serov N.S., Dukhinova M.S., Shtil A.A. Metal-derived nanoparticles in tumor theranostics: Potential and limitations. Journal of Inorganic Biochemistry. 2020. Vol. 209. pp. 111117.
PHOTOCURABLE FILMS BASED ON FIBROIN AND GELATIN FOR REGENERATION OF SKIN COVER
Vasilichin V.A., Tsymbal S.A., Fakhardo A.F., Anastasova E., Marchenko A.S., Shtil A., Vinogradov V.V., Koshel E. Effects of Metal Oxide Nanoparticles on Toll-Like Receptor mRNAs in Human Monocytes. Nanomaterials. 2020. Vol. 10. No. 1. pp. 127.
Комбинированное применение наночастиц оксида меди и N-ацетилцистеина для преодоления лекарственной устойчивости опухолевых клеток
Молекулярные механизмы чувствительности опухолевых клеток к терапевтическому ионизирующему излучению: p53 и CDK8/19
Bessonov I., Moysenovich A., Arkhipova A., Ezernitskaya M., Efremov Y., Solodilov V., Timashev P., Shaytan K., Shtil A., Moisenovich M. The mechanical properties, secondary structure, and osteogenic activity of photopolymerized fibroin. Polymers. 2020. Vol. 12. No. 3. pp. 646.
Grin M., Tikhonov S., Petrova A.S., Pogorilyy V., Noev A., Tatarskiy V.V., Shpakovsky D.B., Milaeva E.R., Kalinina E.V., Chernov N., Shtil A.A., Mironov A., Kaprin A., Filonenko E. New Derivatives of Bacteriopurpurin with Thiolated Au (I) Complexes: Dual Dark-and Light Activated Antitumor Potency. Anti-Cancer Agents in Medicinal Chemistry. 2020. Vol. 20. No. 1. pp. 49-58.
Beniaminov A.D., Chashchina G.V., Livshits M.A., Kechko O.I., Mitkevich V.A., Mamaeva O.K., Tevyashova A.N., Shtil A.A., Shchyolkina A.K., Kaluzhny D.N. Discrimination between G/C Binding Sites by Olivomycin A Is Determined by Kinetics of the Drug-DNA Interaction. International Journal of Molecular Sciences. 2020. Vol. 21. No. 15. pp. 5299.
Belousov A.V., Morozov V.N., Krusanov G.A., Moiseev A.N., Davydov A.S., Shtil A.A., Klimanov V.A., Kolyvanova M.A., Samoylov A.S. The Change in the Linear Energy Transfer of a Clinical Proton Beam in the Presence of Gold Nanoparticles. Biophysics. 2020. Vol. 65. No. 4. pp. 541-547.
Morozov K.V., Kolyvanova M.A., Kartseva M.E., Shishmakova E.M., Dement’Eva O.V., Isagulieva A.K., Salpagarov M.H., Belousov A.V., Rudoy V.M., Shtil A.A., Samoylov A.S., Morozov V.N. Radiosensitization by gold nanoparticles: impact of the size, dose rate, and photon energy. Nanomaterials. 2020. Vol. 10. No. 5. pp. 952.
Markova A.A., Belyaeva E.V., Radchenko A.S., Dmitrieva M.V., Sigan A.L., Shtil A.A., Chkanikov N.D. Perfluorocarbon nanoemulsions containing fluorinated photosensitizer for photodynamic cancer therapy. IOP Conference Series: Materials Science and Engineering. 2020. Vol. 848. No. 1. pp. 012054.
Morozov V.N., Belousov A.V., Zverev V.I., Shtil A.A., Kolyvanova M.A., Krivoshapkin P.V. The Prospects of Metal Oxide Nanoradiosensitizers: The Effect of the Elemental Composition of Particles and Characteristics of Radiation Sources on Enhancement of the Adsorbed Dose. Biophysics. 2020. Vol. 65. No. 4. pp. 533-540.
Anizon F., Giraud F., Ivanova E.S., Kaluzhny D.N., Shtil A., Cisnetti F., Moreau P. Synthesis and biological activities of new pyrrolocarbazole-imidazobenzimidazole conjugates. Tetrahedron Letters. 2020. Vol. 61. No. 30. pp. 152096.
Kostyukov A.A., Egorov A.E., Mestergazi M.G., Shmykova A.M., Podrugina T.A., Borissevitch I.E., Shtil A.A., Kuzmin V.A. Photochemical properties of new bis-cyanine dye as a promising agent for in vivo imaging. Mendeleev Communications. 2020. Vol. 30. No. 4. pp. 442-444.
Sagnou M., Novikov F.N., Ivanova E.S., Alexiou P., Stroylov V.S., Titov I.Y., Tatarskiy V., Vagida M.S., Pelecanou M., Shtil A.A., Chilov G.G. Novel curcumin derivatives as P-glycoprotein inhibitors: molecular modeling, synthesis and sensitization of multidrug resistant cells to doxorubicin. European Journal of Medicinal Chemistry. 2020. Vol. 198. pp. 112331.
Silaeva Y.Y., Kalmykov V.A., Varlamova E.A., Korshunov E.N., Korshunova D.S., Kubekina M.V., Shtil A.A., Roninson I.B., Deykin A.V. Genome editing as an approach to the study of in vivo transcription reprogramming. Doklady Biochemistry and Biophysics. 2020. Vol. 490. No. 1. pp. 43-46.
Gornostaev L.M., Fominykh O.I., Rukovets T.A., Lavrikova T.I., Khalyavina J.G., Shtil A.A., Shunaev A.V., Dunaev S.F., Murashova E.V., Chernyshev V.V. Synthesis of 6b, 11b-dihydroxy-12-methylphenyl-11b, 12-dihydrobenzo-[g] indeno [1, 2-b] indole-5, 6, 7 (6b H)-triones and 2-(3-hydroxy-4, 9-dioxo-4, 9-dihydro-1 H-benzo [f] indol-2-yl) benzamides, their structure and antiproliferative activity. Chemistry of Heterocyclic Compounds. 2020. Vol. 56. No. 1. pp. 47-54.
Nuzhina J., Shtil A.A., Prilepskii A.Y., Vinogradov V.V. Preclinical Evaluation and Clinical Translation of Magnetite-Based Nanomedicines. Journal of Drug Delivery Science and Technology. 2019. Vol. 54. pp. 1773-2247.
Fakhardo A.F., Anastasova E.I., Gabdullina S.R., Solovyeva A.S., Saparova V.B., Chrishtop V.V., Koshevaya E.D., Krivoshapkina E.F., Krivoshapkin P.V., Kiselev G.O., Kalikina P.A., Koshel E.I., Shtil A.A., Vinogradov V.V. Toxicity Patterns of Clinically Relevant Metal Oxide Nanoparticles. ACS Applied Bio Materials. 2019. Vol. 2. No. 10. pp. 4427-4435.
Yurkov D.I., Syromukov S.V., Tatarskiy V., Ivanova E.S., Khamidullina A.I., Yastrebova M.A., Sysoev V.I., Dobrov R.V., Belousov A.V., Morozov V.N., Kolyvanova M.A., Krusanov G.A., Zverev V.I., Shtil A.A. A Unique Prototypic Device for Radiation Therapy: The p53-Independent Antiproliferative Effect of Neutron Radiation. Acta Naturae (англоязычная версия). 2019. Vol. 11. No. 3(42). pp. 99-102.
Ivanova E.S., Tatarskii V.V., Yastrebova M.A., Khamidullina A.I., Shunaev A.V., Kalinina A.A., Zeifman A.A., Novikov F.N., Dutikova Y.V., Chilov G.G., Shtil A.A. PF-114, a novel selective inhibitor of BCR-ABL tyrosine kinase, is a potent inducer of apoptosis in chronic myelogenous leukemia cells. International Journal of Oncology. 2019. Vol. 55. No. 1. pp. 289-297.
Sosonyuk S.E., Peshich A., Tutushkina A.V., Khlevin D.A., Lozinskaya N.A., Gracheva Y.A., Glazunova V.A., Osolodkin D.I., Semenova M.N., Semenov V.V., Palyulin V.A., Proskurnina M.V., Shtil A.A., Zefirov N.S. Synthesis and cytotoxicity of novel simplified eleutherobin analogues as potential antitumour agents. Organic and Biomolecular Chemistry. 2019. Vol. 17. No. 10. pp. 2792-2797.
Volodina Y.L., Dezhenkova L.G., Tikhomirov A.S., Tatarskii V.V., Kaluzhny D.N., Moisenovich A.M., Moisenovich M.M., Isagulieva A.K., Shtil A.A., Tsvetkov V., Shchekotikhin A.E. New anthra[2,3-b]furancarboxamides: a role of positioning of the carboxamide moiety in antitumor properties. European Journal of Medicinal Chemistry. 2019. Vol. 165. pp. 31-45.
Rokitskaya T.I., Khailova L.S., Makarenkov A.V., Shunaev A.V., Tatarskiy V.V., Shtil A.A., Ol'Shevskaya V.A., Antonenko Y.N. Carborane derivatives of 1,2,3-triazole depolarize mitochondria by transferring protons through the lipid part of membranes. Biochimica et Biophysica Acta - Biomembranes. 2019. Vol. 1861. No. 3. pp. 573-583.
Dukhinova M.S., Prilepskii A.Y., Shtil A.A., Vinogradov V.V. Metal Oxide Nanoparticles in Therapeutic Regulation of Macrophage Functions. Nanomaterials. 2019. Vol. 9. No. 11. pp. 1631.
Kalinina E.V., Andreev Y.A., Lybova K., Hasan A.A., Petrova A.S., Chernov N.N., Shtil A.A., Novichkova M.D., Nurmuradov N.K. Thioredoxin/thioredoxin reductase system and redox-dependent regulation of adaptive antioxidant response under formation of cancer cell resistance to cisplatin. FEBS Open Bio. 2019. Vol. 9. No. S1. pp. 333.
Ol'Shevskaya V.A., Alpatova V.M., Radchenko A.S., Tatarskii V.V., Ramonova A.A., Petrova A.S., Tatarskiy V.V., Zaitsev A.V., Kononova E.G., Ikonnikov N.S., Kostyukov A.A., Egorov A.E., Moisenovich M.M., Kuzmin V.A., Bragina N.A., Shtil A.A. Beta-Maleimide substituted meso-arylporphyrins: Synthesis, transformations, physico-chemical and antitumor properties. Dyes and Pigments. 2019. Vol. 171. pp. 107760.
Radchenko A.S., Kostyukov A.A., Markova A.A., Shtil A.A., Nekipelova T.D., Borissevitch I.E., Kuzmin V.A. Photoactivated biscarbocyanine dye with two conjugated chromophores: complexes with albumin, photochemical and phototoxic properties. Photochemical and Photobiological Sciences. 2019. Vol. 18. No. 10. pp. 2461-2468.
Kuzmin V.A., Volnukhin V.A., Egorov A.E., Klimovich O.N., Kostyukov A.A., Nekipelova T.D., Khodot E.N., Shakhmatov V.V., Shevelev A.V., Shibaeva A.B., Shtil A.A. Furodihydroquinolines as Novel Photosensitizers for Photochemotherapy. Russian Journal of Physical Chemistry B. 2019. Vol. 13. No. 6. pp. 893-899.
Belyaeva E.V., Markova A.A., Zakharko M.A., Radchenko A.S., Sigan A.L., Ikonnikov N.S., Shtil A.A., Chkanikov N.D. Chlorin Type Photosensitizers Soluble in Perfluorocarbons: Synthesis and Properties = Фотосенсибилизаторы хлоринового ряда, растворимые в перфторуглеродах: синтез и свойства. Fluorine Notes. 2019. No. 1(122). pp. 7-8.
Salakhova R.T., Pyatakov A.P., Zverev V.I., Pimentel B., Vivas R., Makarova L.A., Perov N.S., Tishin A.M., Shtil A.A., Reis M.S. The frequency dependence of magnetic heating for La0.75Sr0.25MnO3 nanoparticles. Journal of Magnetism and Magnetic Materials. 2019. Vol. 470. pp. 38-40.
Kalinina E.V., Andreev Y.A., Petrova A.S., Shtil A.A., Chernov N.N., Novichkova M.D., Nurmuradov N.K. Trx/TrxR system in redox-dependent regulation under development of cisplatin resistance in cancer cells. Free Radical Biology and Medicine. 2019. Vol. 139. No. 1. pp. 31.
Petrova A.S., Olshevskaya V.A., Zaitsev A.V., Tatarsky V.V., Kalinina E.V., Andreev Y.A., Shtil A.A. New modified chlorin derivative as an antitumor photosensitizer: overcoming antioxidant defense in ovarian carcinoma cells sensitive and resistant to cisplatin. XIII International Conference "Synthesis and Application of Porphyrins and Their Analogues". 2019. pp. 54.
Morozova N.G., Shmendel E.V., Timofeev G.A., Ivanov I.V., Kubasova T.S., Plyavnik N.V., Markova A.A., Maslov M.A., Shtil A.A. New design of cationic alkyl glycoglycerolipids toxic to tumor cells. Mendeleev Communications. 2019. Vol. 29. No. 2. pp. 166-168.
Shtil A.A. Review of Patent Series eBook "Topics in Anti-Cancer Research, vol 6". Current Cancer Therapy Reviews. 2019. Vol. 15. No. 1. pp. 83.
Roninson I.B., Gyorffy B., Mack Z.T., Shtil A.A., Shtutman M.S., Chen M., Broude E.V. Identifying cancers impacted by CDK8/19. Cells. 2019. Vol. 8. No. 8. pp. 821.
Belousov A.V., Morozov V.N., Krusanov G.A., Kolyvanova M.A., Shtil A.A. The Effect of Gold Nanoparticle Surface Modification with Polyethylene Glycol on the Absorbed Dose Distribution upon Irradiation with 137 Cs and 60 Co Photons. Biophysics. 2019. Vol. 64. No. 1. pp. 23–30.
Perevoshchikova K.A., Nichugovskiy A.I., Isagulieva A.K., Morozova N.G., Ivanov I.V., Maslov M.A., Shtil A.A. Synthesis of novel lipophilic tetraamines with cytotoxic activity. Mendeleev Communications. 2019. Vol. 29. No. 6. pp. 616-618.
High–Electron Density Nanomaterials for Theranostics
The combination of copper oxide nanoparticles and N-acetylcysteine as a possible agent for chronic myeloid leukemia treatment
High-Electron Density Nanomaterials for Theranostics
Новая комбинация неорганических композитов и органического соединения для элиминации клеток хронического миелоидного лейкоза
Douara B., Esvan Y.J., Pereira E., Giraud F., Volodina Y.L., Kaluzhny D.N., Shtil A.A., Anizon F., Moreau P. Synthesis and antiproliferative evaluation of glucosylated pyrazole analogs of K252c. Tetrahedron. 2018. Vol. 74. No. 8. pp. 892-901.
Prilepskii A.Y., Fakhardo A.F., Drozdov A.S., Vinogradov V.V., Dudanov I.P., Shtil A.A., Bel'Tyukov P., Shibeko A., Koltsova E., Nechipurenko D., Vinogradov V.V. Urokinase-conjugated magnetite nanoparticles as a promising drug delivery system for targeted thrombolysis: synthesis and preclinical evaluation. ACS Applied Materials and Interfaces. 2018. Vol. 10. No. 43. pp. 36764-36775.
Belousov A.V., Morozov V.N., Krusanov G.A., Kolyvanova M.A., Chernyaev A.P., Shtil A.A. Spectra of secondary particles generated upon virtual irradiation of gold nanosensitizers: Implications for surface modification. Biomedical Physics and Engineering Express. 2018. Vol. 4. No. 4. pp. 045023.
Boron-Based Compounds: Potential and Emerging Applications in Medicine. Cp. 3.3. Carborane Derivatives of Porphyrins and Chlorins for Photodynamic and Boron Neutron Capture Therapies: Synthetic Strategies / Valentina A. Ol'shevskaya Andrei V. Zaitsev Alexander A. Shtil
Высокоэлектроноплотные наноматериалы для онкотераностики
Morozov V.N., Belousov A.V., Krusanov G.A., Kolyvanova M.A., Chernyaev A.P., Shtil A.A. Secondary Electron Spectral Changes of Irradiated Gold Nanoparticle Caused By PEGylation. KnE Energy & Physics. 2018. pp. 278–282.
Shaikhutdinova N.D., Shaikhutdinov T.F., Frolov G.A., Borisova A.I., Akopdzhanov A.G., Shtil A.A. Design of nanodispersed magnetoactive systems for targeted drug delivery. Nanotechnologies in Russia. 2018. Vol. 13. No. 5-6. pp. 317-321.
Beniaminov A.D., Dezhenkova L.G., Mamaeva O.K., Shchyolkina A.K., Tevyashova A.N., Kaluzhny D.N., Shtil A.A. Divalent cations are dispensable for binding to DNA of a novel positively charged olivomycin A derivative. PLoS ONE. 2018. Vol. 13. No. 2. pp. e0191923.
Petrova A., Ol'Shevskaya V., Zaitsev A., Tatarskiy V.V., Kalinina E., Andreev Y., Chernov N., Shtil A.A. Antioxidant mechanisms in ovary adenocarcinoma cells resistant to cisplatin do not rescue from photonecrosis: implications for photodynamic therapy. FEBS Open Bio. 2018. Vol. 8. No. S1. pp. 214.
Antonenko T.A., Shtil A.A., Milaeva E.R. Coordination and Organometallic Compounds with 2,6-di-tert-butylphenol fragments. Synthesis, Structure and Biological Activity. Сборник тезисов всероссийского кластера конференций по неорганической химии "InorgChem2018". 2018. pp. 160.
Kalinina E.V., Andreev Y.A., Lubova K.I., Petrova A.S., Shtil A.A., Chernov N.N. Redox-dependent change in the expression of genes controlling cellular ROS/antioxidants balance under formation of cancer cell resistance to cisplatin. FEBS Open Bio. 2018. Vol. 8. No. S1. pp. 357.
Lukasheva E.V., Kotovshchikov Y.N., Latyshev G.V., Kalinina E.V., Shtil A.A., Kolotova E.S., Lukashev N.V. Transition metals catalyzed reactions–a new approach to the aryl-, azolyl-and triazolylsubstituted steroids–active compounds against human MCF7 breast and SCOV3 ovarian carcinoma cells. FEBS Open Bio. 2018. Vol. 8. No. S1. pp. 238.
Shtil A.A. Meet Our Sectional Editor. Anti-Cancer Agents in Medicinal Chemistry. 2018. Vol. 18. No. 12. pp. 1649.
Belousov A.V., Morozov V.N., Krusanov G.A., Kolyvanova M.A., Chernyaev A.P., Shtil A.A. Modeling the Effect of Surface Modification of Gold Nanoparticles Irradiated with Co-60 on the Secondary Particles Emission Spectrum. Doklady Physics. 2018. Vol. 63. No. 3. pp. 96-99.
Морозов В.Н., Белоусов А.В., Крусанов Г.А., Колыванова М.А., Кривошапкин П.В., Виноградов В.В., Черняев А.П., Штиль А.А. Наноразмерные оксиды тантала, гафния и церия для монохроматических пучков фотонов и брахитерапии. Оптика и спектроскопия. 2018. Т. 125. № 1. С. 101-104.
Tikhomirov A.S., Shtil A.A., Shchekotikhin A.E. Advances in the Discovery of Anthraquinone-Based Anticancer Agents. Recent Patents on Anti-cancer Drug Discovery. 2018. Vol. 13. No. 2. pp. 159-183.
Saparova V.B., Shtil A.A. The role of 53-activators for combined cancer treatment. Альманах научных работ молодых ученых Университета ИТМО. 2018. Vol. 3. pp. 277-278.
Belyaeva E.V., Markova A.A., Kaluzhny D.N., Sigan A.L., Gervitz L.L., Ataeva A.N., Chkanikov N.D., Shtil A.A. Novel Fluorinated Porphyrins Sensitize Tumor Cells to Photodamage in Normoxia and Hypoxia: Synthesis and Biocompatible Formulations. Anti-Cancer Agents in Medicinal Chemistry. 2018. Vol. 18. No. 4. pp. 617-627.
Vinogradov V.V., Drozdov A.S., Mingabudinova L.R., Shabanova E.M., Kolchina N.V., Anastasova E.I., Markova A.A., Shtil A.A., Milichko V.A., Starova G.L., Precker R., Vinogradov A.V., Hey-Hawkins E., Pidko E.A. Composites Based on Heparin and MIL-101(Fe): The Drug Releasing Depot for Anticoagulant Therapy and Advanced Medical Nanofabrication. Journal of Materials Chemistry B. 2018. Vol. 6. No. 16. pp. 2450-2459.
Tikhomirov A.S., Lin C., Volodina Y.L., Dezhenkova L.G., Tatarskiy V.V., Schols D., Shtil A.A., Kaur P., Chueh P.J., Shchekotikhin A.E. New antitumor anthra[2,3-b]furan-3-carboxamides: Synthesis and structure-activity relationship. European Journal of Medicinal Chemistry. 2018. Vol. 148. pp. 128-139.
Morozov V.N., Belousov A.V., Krusanov G.A., Kolyvanova M.A., Krivoshapkin P.V., Vinogradov V.V., Chernyaev A.P., Shtil A.A. Nanosized Particles of Tantalum, Hafnium, and Cerium Oxides Used with Monochromatic Photon Beams and Brachytherapy Sources. Optics and spectroscopy. 2018. Vol. 125. No. 1. pp. 104-106.
Zverev V.I., Pyatakov A.P., Shtil A.A., Tishin A.M. Novel applications of magnetic materials and technologies for medicine. Journal of Magnetism and Magnetic Materials. 2018. Vol. 459. pp. 182-186.
Pimentel B., Caraballo-Vivas R.J., Checca N.R., Zverev V.I., Salakhova R.T., Makarova L.A., Pyatakov A.P., Perov N.S., Tishin A.M., Shtil A.A., Rossi A.L., Reis M.S. Threshold heating temperature for magnetic hyperthermia: controlling the heat exchange with the blocking temperature of magnetic nanoparticles. Journal of Solid State Chemistry. 2018. Vol. 260. pp. 34-38.
Shpakovsky D.B., Shtil A.A., Kharitonashvili E.V., Tyurin V.Y., Antonenko T.A., Nazarov A.A., Osipova V.P., Berberova N.T., Foteeva L.S., Schmidt C., Ott I., Milaeva E.R. The antioxidant 2,6-di-tert-butylphenol moiety attenuates the pro-oxidant properties of the auranofin analogue. Metallomics. 2018. Vol. 10. No. 3. pp. 406-413.
Nadysум G., Tikhomirov A.S., Lin M., Yang Y., Dezhenkova L.G., Chen H., Kaluzhny D.N., Schols D., Shtil A.A., Shchekotikhin A.E., Chueh P.J. Aminomethylation of heliomycin: Preparation and anticancer characterization of the first series of semi-synthetic derivatives. European Journal of Medicinal Chemistry. 2018. Vol. 143. pp. 1553-1562.
Shtil A.A., Ol'Shevskaya V.A., Zaitsev A.V., Radchenko A.S., Petrova A.S., Markova A.A., Miyoshi N., Borissevitch I.E., Kuzmin V.A. Chemical modifications of tetrapyrrole and carbocyanine scaffolds: On the road to optimized antitumor photosensitizers. Photodiagnosis and Photodynamic Therapy. 2017. Vol. 100. No. 17. pp. A24-A25.
Mechanisms of antioxidant protection and photoinduced death in cisplatin-sensitive and-resistant ovarian adenocarcinoma cells
Silva E.R., Pavanelli A.L., Mostaco L.B., Schaberle F.A., Galembeck S.E., Goncalves P.J., Costa E Silva R., Ferreira L.P., Nekipelova T.D., Kostyukov A.A., Radchenko A.S., Shtil A.A., Kuzmin V.A., Borissevitch I.E. Phototransformation of cyanine dye with two chromophores. Effects of oxygen and dye concentration. Journal of Photochemistry and Photobiology A: Chemistry. 2017. Vol. 349. pp. 42-48.
PEGYLATION MODULATES THE SPECTRUM OF SECOND-ARY ELECTRONS UPON IRRADIATION OF GOLD NANO-PARTICLES: A MONTE-CARLO CALCULATION
Vasilyeva S.V., Shtil A.A., Petrova A.S., Balakhnin S.M., Achigecheva P.Y., Stetsenko D.A., Silnikov V.N. Conjugates of phosphorylated zalcitabine and lamivudine with SiO2 nanoparticles: Synthesis by CuAAC click chemistry and preliminary assessment of anti-HIV and antiproliferative activity. Bioorganic and Medicinal Chemistry. 2017. Vol. 25. No. 5. pp. 1696-1702.
Shtil A.A., Miyoshi N., Karaya K., Shimada I., Tanaka H., Sakurai Y., Suzuki M., Zaitsev A.V., Ol’Shevskaya V., Rychkov G., Ono K., Kalinin V. Combination therapy of tumor model with pdt in radiological regions. Journal of International Scientific Publications: Materials, Methods and Technologies (Online). 2017. Vol. 11. pp. 395-402.
Gornostaev L., Tsvetkov V., Markova A., Lavrikova T., Khalyavina Y., Kuznetsova A., Kaluzhny D., Shunayev A., Tsvetkova M., Glazunova V., Chernyshev V., Shtil A.A. The Oxime Derivatives of 1-R-1H-Naphtho[2,3-d][1,2,3]triazole-4,9-dione 2-oxides: Synthesis and Properties. Anti-Cancer Agents in Medicinal Chemistry. 2017. Vol. 17. No. 13. pp. 1814-1823.
DNA nanomachines for targeting nucleic acids in cancer cells
Andreeva Y.I., Drozdov A.S., Fakhardo A.F., Cheplagin N.A., Shtil A.A., Vinogradov V.V. The controllable destabilization route for synthesis of low cytotoxic magnetic nanospheres with photonic response. Scientific Reports. 2017. Vol. 7. pp. 11343.
Volkova Y.A., Chernoburova E.I., Petrova A.S., Shtil A.A., Zavarzin I.V. Reactions of hydrazones derived from oxamic acid thiohydrazides. Phosphorus, Sulfur and Silicon and the Related Elements. 2017. Vol. 192. No. 2. pp. 237-240.
Mechanisms of antioxidant protection and photoinduced death in cisplatin-sensitive and-resistant ovarian adenocarcinoma cells
Kostyukov A.A., Pozdnyakova N.V., Shevelev A.B., Radchenko A.S., Golovina G.V., Klimovich O.N., Shtil’ A.A., Codognato D., Goncalves P., Pavanelli A., Ferreira L.P., Amado A.M., Borisevich Y.E., Kuzmin V.A. Complexes of alpha-fetoprotein and serum albumin with biscarbocyanine dye. High Energy Chemistry. 2017. Vol. 51. No. 3. pp. 233-235.
Kostyukov A.A., Nekipelova T.D., Radchenko A.S., Golovina G.V., Klimovich O.N., Shtil A.A., Codognato D., Goncalves P., Pavanelli A., Ferreira L.P., Amado A.M., Borisevich Y.E., Kuzmin V.A. Triplet states of the complexes of biscarbocyanine dye with albumin. High Energy Chemistry. 2017. Vol. 51. No. 2. pp. 148-150.
Tishin A.M., Shtil A.A., Pyatakov A.P., Zverev V.I. Developing antitumor magnetic hyperthermia: Principles, materials and devices. Recent Patents on Anti-cancer Drug Discovery. 2016. Vol. 11. No. 4. pp. 360-375.
Российская Федерация, Санкт-Петербург
Российская Федерация, Санкт-Петербург